Which type of V/Q mismatch would not benefit from oxygen supplementation?

Prepare for the ACVIM General Board Exam with comprehensive flashcards and in-depth multiple choice questions. Gain insights with detailed explanations and enhance your readiness for success!

Intrapulmonary shunting refers to a situation where blood passes from the right side of the heart to the left side without becoming oxygenated in the lungs due to conditions such as pneumonia, atelectasis, or lung consolidation. In this scenario, blood is effectively "shunted" past the areas of the lung that are functioning normally for gas exchange, meaning that the blood does not pick up adequate oxygen.

When oxygen is administered to a patient with intrapulmonary shunting, the oxygen does not reach the areas of the lung where it can be effectively exchanged into the bloodstream because these areas are poorly ventilated or not ventilated at all. As a result, it does not improve the oxygenation of the blood, leading to hypoxemia. This is a critical distinction because supplemental oxygen is typically effective in cases where there is impaired ventilation in normally perfused areas (like in some types of V/Q mismatch). However, in the case of intrapulmonary shunting, despite the presence of supplemental oxygen, the underlying problem of inadequate ventilation persists, so it does not resolve the mismatch and can be considered ineffective.

In summary, intrapulmonary shunting does not benefit from oxygen supplementation because the condition involves blood flow bypassing ventilated

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