Which drug is used to treat lead toxicity?

Prepare for the ACVIM General Board Exam with comprehensive flashcards and in-depth multiple choice questions. Gain insights with detailed explanations and enhance your readiness for success!

The treatment of lead toxicity often involves chelating agents, which are substances that bind to heavy metals, allowing them to be excreted from the body. In the context of lead toxicity, three different chelating agents can be utilized, and all are correct options for treatment.

Calcium disodium ethylenediaminetetraacetic acid (CaEDTA) is a common chelator used specifically for lead detoxification, particularly when higher levels of contamination are present. It works by binding to lead ions in the bloodstream and facilitating their excretion through the kidneys.

Dimercaprol, also known as British anti-Lewisite, is another chelating agent effective against lead. It forms stable complexes with lead ions and enhances urinary excretion.

D-Penicillamine is another chelating agent that is effective for removing certain heavy metals, including lead. It functions similarly by binding to lead and can help to reduce body burden.

Since all three agents are utilized in the treatment of lead toxicity, the most comprehensive answer is that all listed drugs can serve as treatment options. Each chelator has its specific indications, contraindications, and side effects, but their role in managing lead toxicity is well-established in veterinary and medical practice.

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