Which disease can be misdiagnosed on PARR due to lymphocytosis?

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The choice indicating that Ehrlichia can be misdiagnosed on PARR (PCR for Antigen Receptor Rearrangement) due to lymphocytosis is based on the clinical presentation and laboratory findings associated with Ehrlichiosis. Ehrlichiosis is an infectious disease caused by certain species of Ehrlichia, often transmitted through tick bites. One of the hematological changes that can occur with Ehrlichiosis is lymphocytosis, which might lead to confusion in the diagnosis if only lymphocyte populations are assessed without considering the broader clinical picture and specific testing parameters.

The PARR test is designed to detect clonal populations of lymphocytes, such as those seen in lymphoproliferative disorders. In cases where lymphocytosis is present due to an infectious agent like Ehrlichia, it can mimic the findings in lymphomas or chronic lymphocytic leukemia, potentially leading to a misdiagnosis. Thus, understanding the context of the lymphocytosis—whether it is due to a reactive process from an infection or a result of malignancy—is crucial for accurate diagnosis.

Other conditions listed, such as Canine lymphoma and Chronic lymphocytic leukemia, typically present with characteristic clonal populations that are more easily identified through PARR, making them less likely

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