Which diagnostic test is used for diagnosing masticatory myositis?

The 2M antibody test is specifically designed for diagnosing masticatory myositis, which is an immune-mediated condition affecting the muscles used for chewing in dogs. This test detects antibodies against 2M muscle fibers, which are typically present in animals suffering from this condition. The presence of these antibodies helps confirm a diagnosis of masticatory myositis, as they indicate a targeted autoimmune response against the specific muscle fibers that are affected.

While other diagnostic tests such as muscle biopsy might provide valuable information about muscle histology and inflammation, and serum CK levels can indicate muscle damage, they are not definitive for diagnosing masticatory myositis due to their broader applications in muscle diseases. Similarly, a myogram assesses muscle function but does not directly identify the specific autoimmune process involved in masticatory myositis. Thus, the 2M antibody test serves as a more focused and relevant tool for this condition.