Neutrophils bind to antibody-coated organisms via which receptor?

Neutrophils utilize specific receptors to enhance their immune response against antibody-coated organisms, which is a crucial aspect of the opsonization process. The receptor involved in this process is CD32, also known as FcγRII. This receptor specifically binds to the Fc portion of IgG antibodies that are attached to pathogens. When neutrophils recognize these antibody-coated organisms through CD32, they are activated to phagocytose and destroy the pathogens more effectively.

This receptor is vital for linking the humoral immune response (which produces antibodies) with the cells of the innate immune system (like neutrophils). The interaction between CD32 and IgG is important because it amplifies the ability of neutrophils to respond to infections, helping facilitate the clearing of pathogens that have been marked for destruction.

The other receptor options listed do not play a role in this specific function. CD4 is primarily involved in T-cell activation. CD68 is a marker present on macrophages and some other immune cells, associated with phagocytosis, but it does not mediate binding to antibody-coated organisms. CD28 is a co-stimulatory receptor on T-cells that enhances T-cell activation and is not related to neutrophil opsonization of