In which cells are bile acids conjugated?

Prepare for the ACVIM General Board Exam with comprehensive flashcards and in-depth multiple choice questions. Gain insights with detailed explanations and enhance your readiness for success!

Bile acids are synthesized from cholesterol in the liver and are then conjugated in the hepatocytes. This process involves the addition of an amino acid, such as taurine or glycine, to the bile acids, which increases their solubility and enhances their ability to emulsify dietary fats. This conjugation is essential because it allows for effective digestion and absorption of fats, as well as the proper excretion of bile acids.

While other cell types, such as cholangiocytes, pancreatic acinar cells, and intestinal enterocytes, have important roles in the digestive system, they are not involved in the conjugation of bile acids. Cholangiocytes line the bile ducts and are primarily involved in bile transport and modification. Pancreatic acinar cells are responsible for producing digestive enzymes and bicarbonate but do not deal with bile acid conjugation. Intestinal enterocytes absorb nutrients from digested food but do not perform conjugation of bile acids. Thus, the correct answer is that bile acids are conjugated in hepatocytes.

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